ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
ARTEMIS: RAvulizumab to PRotect PaTients With Chronic Kidney DisEase (CKD) froM Cardiac Surgery Associated Acute Kidney Injury (CSA-AKI) and Subsequent Major Adverse Kidney Events (MAKE): A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study
Study Identifier:D928DC00001
ClinicalTrials.gov Identifier:NCT05746559
EudraCT Identifier:2022-501802-36
Study Details
Medical Condition
Study Phase
Intervention Type
Product
DateMedical ConditionRequirement Information
Date
AgeDateParticipation Requirements
Inclusion Criteria
Exclusion CriteriaInclusion CriteriaThe primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac surgery with CPB.
| Location | Status |
|---|---|
Location United States, Arizona Research Site Tucson, Arizona, United States, 85719 | Status Recruiting |
Location United States, California Research Site Orange, California, United States, 92868 | Status Recruiting |
Location United States, California Research Site San Francisco, California, United States, 94121 | Status Suspended |
Location United States, California Research Site San Francisco, California, United States, 94143 | Status Recruiting |
Location United States, California Research Site Stanford, California, United States, 94305 | Status Recruiting |
Location United States, Colorado Research Site Aurora, Colorado, United States, 80045 | Status Recruiting |
Location United States, District of Columbia Research Site Washington, District of Columbia, United States, 20037-2342 | Status Withdrawn |
Location United States, Florida Research Site Gainesville, Florida, United States, 32610 | Status Withdrawn |
Location United States, Florida Research Site Orlando, Florida, United States, 32804 | Status Withdrawn |
Location United States, Florida Research Site Weston, Florida, United States, 33331 | Status Not yet recruiting |
Location United States, Georgia Research Site Atlanta, Georgia, United States, 30309 | Status Recruiting |
Location United States, Illinois Research Site Chicago, Illinois, United States, 60637 | Status Recruiting |
Location United States, Indiana Research Site Fort Wayne, Indiana, United States, 46804 | Status Withdrawn |
Location United States, Indiana Research Site Indianapolis, Indiana, United States, 46237 | Status Recruiting |
Location United States, Kentucky Research Site Louisville, Kentucky, United States, 40202 | Status Withdrawn |
Location United States, Massachusetts Research Site Boston, Massachusetts, United States, 02115 | Status Recruiting |
Location United States, Massachusetts Research Site Springfield, Massachusetts, United States, 01107 | Status Recruiting |
Location United States, Michigan Research Site Detroit, Michigan, United States, 48201 | Status Recruiting |
Location United States, Missouri Research Site Kansas City, Missouri, United States, 64111 | Status Recruiting |
Location United States, Missouri Research Site Saint Louis, Missouri, United States, 63110 | Status Recruiting |
Location United States, Nebraska Research Site Lincoln, Nebraska, United States, 68506 | Status Withdrawn |
Location United States, New Jersey Research Site Haddon Heights, New Jersey, United States, 08035 | Status Withdrawn |
Location United States, New York Research Site Rochester, New York, United States, 14621 | Status Recruiting |
Location United States, New York Research Site Valhalla, New York, United States, 10595 | Status Recruiting |
Location United States, North Carolina Research Site Durham, North Carolina, United States, 27705 | Status Withdrawn |
Location United States, North Carolina Research Site Winston-Salem, North Carolina, United States, 27157 | Status Not yet recruiting |
Location United States, North Dakota Research Site Fargo, North Dakota, United States, 58102 | Status Recruiting |
Location United States, Ohio Research Site Cleveland, Ohio, United States, 44106 | Status Withdrawn |
Location United States, Ohio Research Site Cleveland, Ohio, United States, 44126 | Status Recruiting |
Location United States, Ohio Research Site Columbus, Ohio, United States, 43210 | Status Recruiting |
Location United States, Pennsylvania Research Site Philadelphia, Pennsylvania, United States, 19104 | Status Withdrawn |
Location United States, Pennsylvania Research Site Philadelphia, Pennsylvania, United States, 19140 | Status Recruiting |
Location United States, Pennsylvania Research Site Philadelphia, Pennsylvania, United States, 19141 | Status Withdrawn |
Location United States, South Carolina Research Site Charleston, South Carolina, United States, 29425 | Status Recruiting |
Location United States, Texas Research Site Dallas, Texas, United States, 75390 | Status Recruiting |
Location United States, Texas Research Site Houston, Texas, United States, 77030 | Status Withdrawn |
Location United States, Texas Research Site Plano, Texas, United States, 75093 | Status Withdrawn |
Location United States, Texas Research Site San Antonio, Texas, United States, 78229 | Status Recruiting |
Location United States, Utah Research Site Salt Lake City, Utah, United States, 84132 | Status Recruiting |
Location United States, Virginia Research Site Charlottesville, Virginia, United States, 22908 | Status Recruiting |
Location United States, Virginia Research Site Richmond, Virginia, United States, 23298 | Status Recruiting |
Location United States, Washington Research Site Seattle, Washington, United States, 98195 | Status Recruiting |
Location United States, Washington Research Site Tacoma, Washington, United States, 98405 | Status Withdrawn |
Location United States, Wisconsin Research Site Wisconsin Rapids, Wisconsin, United States, 54494 | Status Withdrawn |
Location Canada, Alberta Research Site Edmonton, Alberta, Canada, T6G 2B7 | Status Recruiting |
Location Canada, Manitoba Research Site Winnipeg, Manitoba, Canada, R2H 2A6 | Status Recruiting |
Location Canada, New Brunswick Research Site Saint John, New Brunswick, Canada, E2L 4L4 | Status Recruiting |
Location Canada, Ontario Research Site Hamilton, Ontario, Canada, L8L 2X2 | Status Recruiting |
Location Canada, Ontario Research Site Kingston, Ontario, Canada, K7L 2V7 | Status Recruiting |
Location Canada, Ontario Research Site Toronto, Ontario, Canada, M5B 1W8 | Status Recruiting |
Location Canada, Quebec Research Site Montreal, Quebec, Canada, H2X 0C1 | Status Recruiting |
Location Canada, Quebec Research Site Montreal, Quebec, Canada, H4J 1C5 | Status Recruiting |
Location Canada, Quebec Research Site Montréal, Quebec, Canada, H1T 1C8 | Status Recruiting |
Location France Research Site Bordeaux Cedex, France, 33074 | Status Recruiting |
Location France Research Site Toulouse Cedex 3, France, 31076 | Status Recruiting |
Location Japan Research Site Bunkyo-ku, Japan, 113-8431 | Status Recruiting |
Location Japan Research Site Chuo-ku, Japan, 104-8560 | Status Recruiting |
Location Japan Research Site Kamakura-shi, Japan, 247-8533 | Status Recruiting |
Location Japan Research Site Kawasaki-shi, Japan, 216-8511 | Status Recruiting |
Location Japan Research Site Minato-ku, Japan, 105-8470 | Status Recruiting |
Location Japan Research Site Sagamihara-shi, Japan, 252-0375 | Status Recruiting |
Location Japan Research Site Suginami, Japan, 168-0065 | Status Recruiting |
Location Japan Research Site Urayasu, Japan, 279-0001 | Status Recruiting |
Location Portugal Research Site Coimbra, Portugal, 3000-075 | Status Not yet recruiting |
Location Portugal Research Site Lisboa, Portugal, 1169-024 | Status Not yet recruiting |
Location Portugal Research Site Lisboa, Portugal, 1649-035 | Status Not yet recruiting |
Location Spain Research Site A Coruna, Spain, 15006 | Status Recruiting |
Location Spain Research Site Córdoba, Spain, 14004 | Status Recruiting |
Location Spain Research Site Madrid, Spain, 28040 | Status Recruiting |
Location Spain Research Site Madrid, Spain, 28041 | Status Recruiting |
Location Spain Research Site Majadahonda, Spain, 28250 | Status Recruiting |
Location Spain Research Site Navarra, Spain, 31190 | Status Recruiting |
Location Spain Research Site Santander, Spain, 39008 | Status Withdrawn |
Location Spain Research Site Sevilla, Spain, 41071 | Status Recruiting |
Location Spain Research Site Valencia, Spain, 46010 | Status Recruiting |
Location Spain Research Site Valladolid, Spain, 47003 | Status Recruiting |
Location United Kingdom Research Site Cambridge, United Kingdom, CB2 0AY | Status Recruiting |
Location United Kingdom Research Site Clydebank, United Kingdom, G81 4DY | Status Recruiting |
Location United Kingdom Research Site Edinburgh, United Kingdom, EH16 4SA | Status Recruiting |
Location United Kingdom Research Site London, United Kingdom, SE1 9RT | Status Recruiting |
Location United Kingdom Research Site London, United Kingdom, SW17 0QT | Status Recruiting |
Location United Kingdom Research Site London, United Kingdom, W12 0HS | Status Recruiting |
Location United Kingdom Research Site Newcastle upon Tyne, United Kingdom, NE7 7DN | Status Recruiting |
